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首頁 > 產品中心 > 抗體 > 內參抗體 > abs132004Rabbit anti-GAPDH Polyclonal Antibody

Rabbit anti-GAPDH Polyclonal Antibody

簡要描述:Rabbit anti-GAPDH Polyclonal Antibody的應用WB: 1:3000-1:30000, IHC: 1:200, IF: 1:200, ELISA(peptide): 1:20000-1:40000

  • 產品型號:abs132004
  • 廠商性質:生產廠家
  • 更新時間:2025-02-07
  • 訪  問  量:1698

詳細介紹

品牌absin貨號abs132004
規格100ug供貨周期現貨
主要用途WB: 1:3000-1:30000, IHC: 1:200應用領域化工,生物產業,農業,制藥,綜合

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截止2024年7月,該產品引用文獻120+篇!!


名稱:Rabbit anti-GAPDH Polyclonal Antibody

宿主:Rabbit

反應種屬:Human, Mouse, Rat, Pig, Bovine, Goat, Monkey, Chicken

免疫原:A synthesized peptide derived from human GAPDH.

純化方法:The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin.


分子量:

Predicted molecular weight: 36kD
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.


背景說明:

Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Nuclear functions are probably due to the nitrosylase activity that mediates cysteine S-nitrosylation of nuclear target proteins such as SIRT1, HDAC2 and PRKDC. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubules (By similarity). Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. Upon interferon-gamma treatment assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation.


細胞定位:

Cytoskeleton;Cytosol;Extracellular region or secreted;Nucleus;Plasma Membrane;


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