欧美激情在线看,国产成人黄网在线免,久久成人在线视频,制服丝袜护士久久久久久

全國服務咨詢熱線:

Products產品中心
首頁 > 產品中心 > 抗體 > 內參抗體 > abs130609GAPDH Antibody(50ug)

GAPDH Antibody(50ug)

簡要描述:愛必信特色產品線:
生化試劑(60萬種)、抗體(10萬種)、細胞因子、二抗、ECL發光液、蛋白marker、激動劑、抑制劑、凋亡試劑盒、BSA、動植物提取物、蛋白酶K...

  • 產品型號:abs130609
  • 廠商性質:生產廠家
  • 更新時間:2025-02-07
  • 訪  問  量:1306

詳細介紹

品牌absin供貨周期一周
概述
描述

Glyceraldehyde 3 phosphate dehydrogenase (GAPDH) is well known as one of the key enzymes involved in glycolysis. GAPDH is constitutively abundant expressed in almost cell types at high levels, therefore antibodies against GAPDH are useful as loading controls for Western Blotting. Some pathology factors, such as hypoxia and diabetes, increased or decreased GAPDH expression in certain cell types.

別名GAPDH, A1 40 kd subunit, Activator 1 40 kd subunit, G3PD, GAPD, G3pdh, Rfc40, Rf-c 40 kd subunit
克隆類別Polyclonal
反應種屬 

H, Mk
來源宿主Rabbit
應用

WB: 1:5000~1:50000
特異性GAPDH antibody detects endogenous levels of total GAPDH protein from human and monkey.Is unsuitable for MOUSE and RAT,not yet tested in other species.
性能
保存方法Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
濃度1mg/ml
分子量37KD
功能Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Nuclear functions are probably due to the nitrosylase activity that mediates cysteine S-nitrosylation of nuclear target proteins such as SIRT1, HDAC2 and PRKDC. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubules (By similarity). Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. Upon interferon-gamma treatment assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation.
亞細胞定位Cytoplasm,Cytosol,Nucleus,Cytoplasm,Perinuclear region,Membrane,Cytoplasm,Cytoskeleton,Note:Translocates to the nucleus following S-nitrosylation and interaction with SIAH1, which contains a nuclear localization signal (By similarity). Postnuclear and Perinuclear regions.
序列MGKVKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTV KAENGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVI ISAPSADAPMFVMGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHA ITATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTANV SVVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAGAG IALNDHFVKLISWYDNEFGYSNRVVDLMAHMASKE

實驗結果圖

Western blot analysis of Hela (1), Jurket (2), and COS-7(3) with GAPDH antibody(1;50000)

Western blot analysis of Hela (1), Jurket (2), and COS-7(3) with GAPDH antibody(1;50000)

產品咨詢

留言框

  • 產品:

  • 您的單位:

  • 您的姓名:

  • 聯系電話:

  • 常用郵箱:

  • 省份:

  • 詳細地址:

  • 補充說明:

  • 驗證碼:

    請輸入計算結果(填寫阿拉伯數字),如:三加四=7
愛必信(上海)生物科技有限公司
地址:上海市浦東新區新浩路58號申江科創園18棟
郵箱:wulan@absin.cn
傳真:
關注我們
歡迎您關注我們的微信公眾號了解更多信息:
歡迎您關注我們的微信公眾號
了解更多信息