欧美激情在线看,国产成人黄网在线免,久久成人在线视频,制服丝袜护士久久久久久

全國(guó)服務(wù)咨詢熱線:

Products產(chǎn)品中心

FCGR3A/CD16a (C-6His)

簡(jiǎn)要描述:愛(ài)必信特色產(chǎn)品線(全部現(xiàn)貨):
二抗、標(biāo)簽抗體、對(duì)照抗體;WB相關(guān):ECL發(fā)光液、預(yù)染marker、預(yù)制膠;IHC相關(guān):二抗試劑盒、組化筆;IP/CoIP試劑盒;細(xì)胞因子、信號(hào)通路調(diào)節(jié)劑;血清、BSA、蛋白酶K、CTB、TTX、CEE;凋亡試劑盒、呼吸爆發(fā)試劑盒;動(dòng)植物提取物...

  • 產(chǎn)品型號(hào):abs04013
  • 廠商性質(zhì):生產(chǎn)廠家
  • 更新時(shí)間:2025-02-07
  • 訪  問(wèn)  量:1116

詳細(xì)介紹

品牌absin規(guī)格10ug
供貨周期一周
概述
描述Recombinant Human Fc gamma RIIIA is produced by our Mammalian expression system and the target gene encoding Gly17-Gln208 is expressed with a 6His tag at the C-terminus.
別名Low Affinity Immunoglobulin Gamma Fc Region Receptor III-A, CD16a Antigen, Fc-Gamma RIII-Alpha, Fc-Gamma RIII, Fc-gamma RIIIa, FcRIII, FcRIIIa, FcR-10, IgG Fc Receptor III-2, CD16a, FCGR3A, CD16A, FCG3, FCGR3, IGFR3
形態(tài)Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
來(lái)源Human Cells
氨基酸序列GMRTEDLPKAVVFLEPQWYRVLEKDSVTLKCQGAYSPEDNSTQWFHNESLISSQASSYFIDAATV DDSGEYRCQTNLSTLSDPVQLEVHIGWLLLQAPRWVFKEEDPIHLRCHSWKNTALHKVTYLQNGK GRKYFHHNSDFYIPKATLKDSGSYFCRGLVGSKNVSSETVNITITQGLAVSTISSFFPPGYQHHH HHH
內(nèi)毒素水平Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test.
Accession #P08637
性能
背景Receptors for the Fc region of immunoglobin G (FcγR) are divided into three classes and FcγRIII is a multifunctional, low/intermediate affinity receptor. In humans, FcγRIII is expressed as two distinct forms (FcγRIIIA and FcγRIIIB) that are encoded by two different but highly homologous genes in a cell type-specific manner. FcγRIIIB is a low-affinity, GPI-linked receptor expressed by neutrophils and eosinophils, whereas FcγRIIIA is an intermediate affinity polypeptide-anchored transmembrane glycoprotein expressed by a subset of T lymphocytes, natural killer (NK) cells, monocytes, and macrophages. The FcγRIIIA receptor is involved in phagocytosis, secretion of enzymes, inflammatory mediators, antibody-dependent cellular cytotoxicity (ADCC), mast cell degranulation, and clearance of immune complexes. FcγRIIIA has an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain and delivers an activation signal in the immune responses. Aberrant expression or mutations in this gene is implicated in susceptibility to recurrent viral infections, systemic lupus erythematosus, and alloimmune neonatal neutropenia. In humans, it is a 50 -70 kD type I transmembrane activating receptor. The FcγRIIIA cDNA encodes 254 amino acid including a 16aa signal sequence, 191 amino acid ECD with two C2-type Ig-like domains, five potential N-glycosylation sites, a 22 amino acid transmembrane sequence and a 25 amino acid cytoplasmic domain.
溶解方法Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
保存方法Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
純度Greater than 95% as determined by reducing SDS-PAGE.

產(chǎn)品咨詢

留言框

  • 產(chǎn)品:

  • 您的單位:

  • 您的姓名:

  • 聯(lián)系電話:

  • 常用郵箱:

  • 省份:

  • 詳細(xì)地址:

  • 補(bǔ)充說(shuō)明:

  • 驗(yàn)證碼:

    請(qǐng)輸入計(jì)算結(jié)果(填寫(xiě)阿拉伯?dāng)?shù)字),如:三加四=7
愛(ài)必信(上海)生物科技有限公司
地址:上海市浦東新區(qū)新浩路58號(hào)申江科創(chuàng)園18棟
郵箱:wulan@absin.cn
傳真:
關(guān)注我們
歡迎您關(guān)注我們的微信公眾號(hào)了解更多信息:
歡迎您關(guān)注我們的微信公眾號(hào)
了解更多信息