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首頁 > 產品中心 > 細胞生物學 > 重組蛋白 > abs04106MMP-3 （C-6His）

MMP-3 （C-6His）

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  • 產品型號：abs04106
  • 廠商性質：生產廠家
  • 更新時間：2025-02-07
  • 訪  問  量：1085

詳細介紹

品牌absin規格10ug
供貨周期一周
概述
描述Recombinant Human Matrix Metalloproteinase-3 is produced by our Mammalian expression system and the target gene encoding Tyr18-Cys477 is expressed with a 6His tag at the C-terminus.
別名Stromelysin-1, SL-1, Matrix metalloproteinase-3, MMP-3, Transin-1, MMP3, STMY1
形態Supplied as a 0.2 μm filtered solution of 20mM TrisHCl, 150mM NaCl, 0.05% Brij35, 10% Glycerol, pH 7.5.
來源Human Cells
氨基酸序列YPLDGAARGEDTSMNLVQKYLENYYDLEKDVKQFVRRKDSGPVVKKIREMQKFLGLEVTGKLDSD TLEVMRKPRCGVPDVGHFRTFPGIPKWRKTHLTYRIVNYTPDLPKDAVDSAVEKALKVWEEVTPL TFSRLYEGEADIMISFAVREHGDFYPFDGPGNVLAHAYAPGPGINGDAHFDDDEQWTKDTTGTNL FLVAAHEIGHSLGLFHSANTEALMYPLYHSLTDLTRFRLSQDDINGIQSLYGPPPDSPETPLVPT EPVPPEPGTPANCDPALSFDAVSTLRGEILIFKDRHFWRKSLRKLEPELHLISSFWPSLPSGVDA AYEVTSKDLVFIFKGNQFWAIRGNEVRAGYPRGIHTLGFPPTVRKIDAAISDKEKNKTYFFVEDK YWRFDEKRNSMEPGFPKQIAEDFPGIDSKIDAVFEEFGFFYFFTGSSQLEFDPNAKKVTHTLKSN SWLNCVDHHHHHH
內毒素水平Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test.
Accession #P08254
性能
背景MMP3 is a member of the matrix metalloproteinase (MMP) family whose members are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, tissue remodeling, and disease processes including arthritis and metastasis. The MMP-3 enzyme degrades collagen types II, III, IV, IX, and X, proteoglycans, fibronectin, laminin, and elastin. In addition, MMP-3 can also activate other MMPs such as MMP-1, MMP-7, and MMP-9, rendering MMP-3 crucial in connective tissue remodeling.[3] The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation.
保存方法Store at < -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
純度Greater than 95% as determined by reducing SDS-PAGE.

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愛必信（上海）生物科技有限公司
地址：上海市浦東新區新浩路58號申江科創園18棟
郵箱：wulan@absin.cn
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