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首頁 > 產品中心 > 細胞生物學 > 重組蛋白 > abs04047Recombinant Human Interleukin-17A/IL-17A

Recombinant Human Interleukin-17A/IL-17A

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二抗、標簽抗體、對照抗體；WB相關：ECL發光液、預染marker、預制膠；IHC相關：二抗試劑盒、組化筆；IP/CoIP試劑盒；細胞因子、信號通路調節劑；血清、BSA、蛋白酶K、CTB、TTX、CEE；凋亡試劑盒、呼吸爆發試劑盒；動植物提取物...

  • 產品型號：abs04047
  • 廠商性質：生產廠家
  • 更新時間：2025-02-07
  • 訪  問  量：1267

詳細介紹

品牌absin規格10ug
供貨周期一周
概述
描述Recombinant Human Interleukin-17A is produced by our E.coli expression system and the target gene encoding Ile20-Ala155 is expressed.
別名Interleukin-17A, IL-17, IL-17A, Cytotoxic T-Lymphocyte-Associated Antigen 8, CTLA-8, IL17A, CTLA8, IL17
形態Lyophilized from a 0.2 μm filtered solution of 20mM PB, pH 7.4.
來源E.coli
氨基酸序列MIVKAGITIPRNPGCPNSEDKNFPRTVMVNLNIHNRNTNTNPKRSSDYYNRSTSPWNLHRNEDPE RYPSVIWEAKCRHLGCINADGNVDYHMNSVPIEILVLRREPPHCPNSFRLEKILVSVGCTCVT PIVHHVA
內毒素水平Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test.
Accession #Q16552
性能
背景Interleukin-17 is a potent pro-inflammatory cytokine produced by activated memory T cells. There are at least six members of the IL-17 family in humans and in mice. As IL-17 shares properties with IL-1 and TNF-alpha, it may induce joint inflammation and bone and cartilage destruction. This cytokine is found in synovial fluids of patients with rheumatoid arthritis, and produced by rheumatoid arthritis synovium. It increases IL-6 production, induces collagen degradation and decreases collagen synthesis by synovium and cartilage and proteoglycan synthesis in cartilage. IL-17 is also able to increase bone destruction and reduce its formation. Blocking of interleukin-17 with specific inhibitors provides a protective inhibition of cartilage and bone degradation.
溶解方法Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
保存方法Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
純度Greater than 95% as determined by reducing SDS-PAGE. 

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